Estimation of the Youden Index and its associated cutoff point.

@article{Fluss2005EstimationOT,
  title={Estimation of the Youden Index and its associated cutoff point.},
  author={Ronen Fluss and David Faraggi and Benjamin Reiser},
  journal={Biometrical journal. Biometrische Zeitschrift},
  year={2005},
  volume={47 4},
  pages={458-72}
}
The Youden Index is a frequently used summary measure of the ROC (Receiver Operating Characteristic) curve. It both, measures the effectiveness of a diagnostic marker and enables the selection of an optimal threshold value (cutoff point) for the marker. In this paper we compare several estimation procedures for the Youden Index and its associated cutoff point. These are based on (1) normal assumptions; (2) transformations to normality; (3) the empirical distribution function; (4) kernel… CONTINUE READING
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