Estimation of the 18F-FDG input function in mice by use of dynamic small-animal PET and minimal blood sample data.

@article{Ferl2007EstimationOT,
  title={Estimation of the 18F-FDG input function in mice by use of dynamic small-animal PET and minimal blood sample data.},
  author={Gregory Z. Ferl and Xiaoli Zhang and Hsiao-Ming Wu and Michael C. Kreissl and Sung-Cheng Huang},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2007},
  volume={48 12},
  pages={2037-45}
}
UNLABELLED Derivation of the plasma time-activity curve in murine small-animal PET studies is a challenging task when tracers that are sequestered by the myocardium are used, because plasma time-activity curve estimation usually involves drawing a region of interest within the area of the reconstructed image that corresponds to the left ventricle (LV) of the heart. The small size of the LV relative to the resolution of the small-animal PET system, coupled with spillover effects from adjacent… CONTINUE READING
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