Estimation of relative skin sensitizing potency using the local lymph node assay: a comparison of formaldehyde with glutaraldehyde.

@article{Hilton1998EstimationOR,
  title={Estimation of relative skin sensitizing potency using the local lymph node assay: a comparison of formaldehyde with glutaraldehyde.},
  author={Jennifer Hilton and Rebecca Jane Dearman and Peter J. Harvey and P. Evans and David A Basketter and I A N Kimber},
  journal={American journal of contact dermatitis : official journal of the American Contact Dermatitis Society},
  year={1998},
  volume={9 1},
  pages={29-33}
}
BACKGROUND Chemicals vary considerably in their intrinsic ability to cause allergic contact dermatitis. Presently, there are no experimental methods available for the quantitative assessment of the relative sensitizing potency of chemical allergens. OBJECTIVE The objective of the investigations described here was to evaluate the use of the local lymph node assay for determining the relative skin sensitizing potential of chemicals. This has been addressed by comparing the sensitizing potency… CONTINUE READING

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