Estimation of insulin sensitivity and glucose clearance from minimal model: new insights from labeled IVGTT.

Abstract

The "minimal model" of glucose disappearance provides noninvasive estimates of insulin sensitivity and glucose effectiveness from an intravenous glucose tolerance test (IVGTT). However, this model does not allow the separation of glucose production from utilization. To overcome this limitation, labeled glucose was injected along with cold glucose in six… (More)

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