Estimation of infectious dose and viral shedding rates for infectious pancreatic necrosis virus in Atlantic salmon, Salmo salar L., post-smolts.

@article{Urquhart2008EstimationOI,
  title={Estimation of infectious dose and viral shedding rates for infectious pancreatic necrosis virus in Atlantic salmon, Salmo salar L., post-smolts.},
  author={Katy L Urquhart and Alexander G. Murray and Ann Gregory and M. O'Dea and Lorna Ann Munro and David A Smail and Aileen M Shanks and Robert S Raynard},
  journal={Journal of fish diseases},
  year={2008},
  volume={31 12},
  pages={879-87}
}
Infectious dose and shedding rates are important parameters to estimate in order to understand the transmission of infectious pancreatic necrosis virus (IPNV). Bath challenge of Atlantic salmon post-smolts was selected as the route of experimental infection as this mimics a major natural route of exposure to IPNV infection. Doses ranging from 10(2) to 10(-4) 50% end-point tissue culture infectious dose (TCID(50)) mL(-1) sea water were used to estimate the minimum infectious dose for a Scottish… CONTINUE READING