Estimation of individual admixture: analytical and study design considerations.

@article{Tang2005EstimationOI,
  title={Estimation of individual admixture: analytical and study design considerations.},
  author={Hua Tang and Jie Peng and Pei Xin Wang and Neil J. Risch},
  journal={Genetic epidemiology},
  year={2005},
  volume={28 4},
  pages={289-301}
}
The genome of an admixed individual represents a mixture of alleles from different ancestries. In the United States, the two largest minority groups, African-Americans and Hispanics, are both admixed. An understanding of the admixture proportion at an individual level (individual admixture, or IA) is valuable for both population geneticists and epidemiologists who conduct case-control association studies in these groups. Here we present an extension of a previously described frequentist… CONTINUE READING
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