Estimation of correlation of lactate dehydrogenase subunits mole quota based on differences in substrate inhibition

Abstract

A kinetic method of estimating the mole quota ratios of the human lactate dehydrogenase (LDH) H and M subunits based on differences in substrate inhibition of LDH isoenzymes by lactate is proposed. Stability of kinetic constants for a prolonged period of time is demonstrated. The dependence of the activity ratios on the contribution of the mole quota of the… (More)
DOI: 10.1007/BF00225454

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