Estimation of Fine-Scale Recombination Intensity Variation in the white–echinus Interval of D. melanogaster

@article{Singh2009EstimationOF,
  title={Estimation of Fine-Scale Recombination Intensity Variation in the white–echinus Interval of D. melanogaster},
  author={Nadia D. Singh and Charles F. Aquadro and Andrew G. Clark},
  journal={Journal of Molecular Evolution},
  year={2009},
  volume={69},
  pages={42-53}
}
Accurate assessment of local recombination rate variation is crucial for understanding the recombination process and for determining the impact of natural selection on linked sites. In Drosophila, local recombination intensity has been estimated primarily by statistical approaches, by estimating the local slope of the relationship between the physical and genetic maps. However, these estimates are limited in resolution and, as a result, the physical scale at which recombination intensity varies… CONTINUE READING