Estimation of Allele Frequencies in Indigenous Populations of Siberia Based on Pedigree Data


Procedure is described to estimate allele frequencies in indigenous populations of Siberia using phenotype data not only for “pure-blood” representatives of the ethnic groups examined, but also for the descendants of mixed marriages. Implementation of the method requires reconstruction of the pedigree structure for the sample examined. Inclusion of the data… (More)
DOI: 10.1023/A:1012513226719


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