Estimating the time course of evoked quantal release at the frog neuromuscular junction using end-plate current latencies.

@article{Baldo1986EstimatingTT,
  title={Estimating the time course of evoked quantal release at the frog neuromuscular junction using end-plate current latencies.},
  author={George J. Baldo and Ira S. Cohen and William G. Van der Kloot},
  journal={The Journal of physiology},
  year={1986},
  volume={374},
  pages={503-13}
}
The use of end-plate current (e.p.c.) latency measurements to estimate the time course of the stochastic probabilistic process governing evoked release was investigated in the sciatic nerve-sartorius muscle preparation of the frog, Rana pipiens. We also examined the possibility that the release of a quantum depresses or enhances the subsequent release of additional quanta. Muscle end-plates were voltage clamped at 3-4 degrees C. Quantal release was restricted to a short, or localized, region of… CONTINUE READING
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