Estimating the size of the capillary-to-fiber interface in skeletal muscle: a comparison of methods.

@article{Hepple2001EstimatingTS,
  title={Estimating the size of the capillary-to-fiber interface in skeletal muscle: a comparison of methods.},
  author={Russell T Hepple and Odile Mathieu-Costello},
  journal={Journal of applied physiology},
  year={2001},
  volume={91 5},
  pages={2150-6}
}
Current evidence suggests that the size of the capillary-to-fiber (C/F) interface is a major determinant of O2 flux into muscle fibers, and methods have been developed for estimating the size of this region via the C/F perimeter ratio in perfusion-fixed material (Mathieu-Costello O, Ellis CG, Potter RF, MacDonald IC, and Groom AC. Am J Physiol Heart Circ Physiol 261: H1617-H1625, 1991) and the quotient of the individual, fiber-based C/F number ratio and fiber perimeter (C/F perimeter exchange… CONTINUE READING

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