Estimating the rate of accumulating drug resistance mutations in the HIV genome.

Abstract

OBJECTIVE HIV mutation accumulation has great implications for pharmacoeconomics and clinical care, yet scarcity of data has hindered its representation in decision analytic models. Our objective is to determine the accuracy with which mutation accumulation and other unmeasured parameters could be estimated during model calibration. METHODS We used a… (More)

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@article{Braithwaite2007EstimatingTR, title={Estimating the rate of accumulating drug resistance mutations in the HIV genome.}, author={R. Scott Braithwaite and Steven Shechter and Chung-Chou H. Chang and Andrew Schaefer and Mark S. Roberts}, journal={Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research}, year={2007}, volume={10 3}, pages={204-13} }