Estimating the pattern of nucleotide substitution

@article{Yang1994EstimatingTP,
  title={Estimating the pattern of nucleotide substitution},
  author={Ziheng Yang},
  journal={Journal of Molecular Evolution},
  year={1994},
  volume={39},
  pages={105-111}
}
Knowledge of the pattern of nucleotide substitution is important both to our understanding of molecular sequence evolution and to reliable estimation of phylogenetic relationships. The method of parsimony analysis, which has been used to estimate substitution patterns in real sequences, has serious drawbacks and leads to results difficult to interpret. In this paper a model-based maximum likelihood approach is proposed for estimating substitution patterns in real sequences. Nucleotide… CONTINUE READING
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References

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SHOWING 1-10 OF 35 REFERENCES

Statistical tests of models of DNA substitution

  • Journal of Molecular Evolution
  • 1993
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Molecular evolutionary rates of oncogenes

  • Journal of Molecular Evolution
  • 1987
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Estimation of the number of nucleotide substitutions when there are strong transition-transversion and G + C-content biases

K Tamura
  • Mol Biol Evol
  • 1992
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Evolutionary trees from DNA sequences: A maximum likelihood approach

  • Journal of Molecular Evolution
  • 1981
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Maximum likelihood estimation of phylogeny from DNA sequences when substitution rates differ over sites

Z Yang
  • Mol Biol Evol
  • 1993
VIEW 1 EXCERPT

Goj obori T (1992) Patterns of nucleotide substitutions

T Imanishi
  • 1992
VIEW 1 EXCERPT

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