Estimating the parameters of selection on nonsynonymous mutations in Drosophila pseudoobscura and D. miranda.

@article{Haddrill2010EstimatingTP,
  title={Estimating the parameters of selection on nonsynonymous mutations in Drosophila pseudoobscura and D. miranda.},
  author={Penelope R. Haddrill and Laurence Loewe and Brian Charlesworth},
  journal={Genetics},
  year={2010},
  volume={185 4},
  pages={1381-96}
}
We present the results of surveys of diversity in sets of >40 X-linked and autosomal loci in samples from natural populations of Drosophila miranda and D. pseudoobscura, together with their sequence divergence from D. affinis. Mean silent site diversity in D. miranda is approximately one-quarter of that in D. pseudoobscura; mean X-linked silent diversity is about three-quarters of that for the autosomes in both species. Estimates of the distribution of selection coefficients against… CONTINUE READING

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