Estimating the number of release sites and probability of firing within the nerve terminal by statistical analysis of synaptic charge.

@article{Viele2003EstimatingTN,
  title={Estimating the number of release sites and probability of firing within the nerve terminal by statistical analysis of synaptic charge.},
  author={Kert Viele and Arnold J. Stromberg and Robin L Cooper},
  journal={Synapse},
  year={2003},
  volume={47 1},
  pages={15-25}
}
Investigating the function of individual synapses is essential to understanding the mechanisms that influence the efficacy of chemical synaptic transmission. The known simplicity of the synaptic structure at the crayfish neuromuscular junction (NMJ) and its quantal nature of release allows an assessment of discrete synapses within the motor nerve terminals. Our goal in this article is to investigate the effect of the stimulation frequency on the number of active release sites (n) and the… CONTINUE READING