Estimating the lost benefits of antiretroviral drug use in South Africa.

@article{Chigwedere2008EstimatingTL,
  title={Estimating the lost benefits of antiretroviral drug use in South Africa.},
  author={Pride Chigwedere and George R. Seage and Sofia Gruskin and Tun‐Hou Lee and Max Essex},
  journal={Journal of acquired immune deficiency syndromes},
  year={2008},
  volume={49 4},
  pages={
          410-5
        }
}
South Africa is one of the countries most severely affected by HIV/AIDS. At the peak of the epidemic, the government, going against consensus scientific opinion, argued that HIV was not the cause of AIDS and that antiretroviral (ARV) drugs were not useful for patients and declined to accept freely donated nevirapine and grants from the Global Fund. Using modeling, we compared the number of persons who received ARVs for treatment and prevention of mother-to-child HIV transmission between 2000… 

The adequacy of policy responses to the treatment needs of South Africans living with HIV (1999-2008): a case study

  • J. Gow
  • Medicine, Political Science
    Journal of the International AIDS Society
  • 2009
TLDR
The movement towards a national ART programme in South Africa was an ambitious undertaking, the likes of which had not been contemplated before in public health in Africa, but it failed because of lack of political commitment and inadequate public health system capacity.

Prevention of mother-to-child transmission in South Africa: an ever-changing landscape

TLDR
The evolution of the HIV epidemic in South Africa is discussed, and a historical overview of the struggle to establish a national PMTCT is given, and the impact of delaying PMT CT and treatment programmes on infant and maternal health is given.

Provision of Antiretroviral Therapy in South Africa: The Nuts and Bolts

TLDR
South Africa is a test case of whether a large-scale public health programme can boast of success in the face of numerous other health-system challenges and challenges include increasing detection within communities, linkage and retention in care, while strengthening operational support functions.

HIV/AIDS in South Africa: how many people died from the disease between 1997 and 2010?

TLDR
Empirically based estimates confirm the considerable loss of life from HIV/AIDS and should be used for calibrating models of the AIDS epidemic which generally appear too low for infants but too high for other ages.

Effect of Human Immunodeficiency Virus Treatment on Maternal Mortality at a Tertiary Center in South Africa: A 5-Year Audit

TLDR
In Johannesburg, HIV remains the major cause of maternal mortality despite integration of antiretroviral treatment into prenatal services, and maternal health services should target barriers to uptake of HIV treatment and care.

Population-level associations between antiretroviral therapy scale-up and all-cause mortality in South Africa

TLDR
The scale-up of antiretroviral therapy in South Africa was associated with a significant reduction in national all-cause mortality and the associated decrease in mortality the year after treatment reporting was seen in both adults and children, and men and women.

A Political and Social History of HIV in South Africa

TLDR
The story of the HIV and AIDS response in South Africa over the past 5 years is one of great progress after almost a decade of complex and tragic denialism that united civil society in a way not seen since the opposition to apartheid.

HIV treatment in South Africa : the challenges of an increasingly successful antiretroviral programme : service delivery

TLDR
This chapter examines the political policy programmatic and other issues surrounding the initiation and expansion of the ART programme in South Africa.

Income Status and Education as Predictors of HIV Transmission in South Africa

TLDR
It is argued that income status and education act as risk factors for HIV through their effects on individual behaviour, while also being adversely impacted due to the occurrence of infection.
...

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