Estimating the information value of polymorphic sites using pooled sequences


High-throughput sequencing is a cost effective method for identifying genetic variation, and it is currently in use on a large scale across the field of biology, including ecology and population genetics. Correctly identifying variable sites and allele frequencies from sequencing data remains challenging, in large part due to artifacts and biases inherent… (More)
DOI: 10.1186/1471-2164-15-S6-S20


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