Estimating the in-vivo HIV template switching and recombination rate

@article{Cromer2016EstimatingTI,
  title={Estimating the in-vivo HIV template switching and recombination rate},
  author={Deborah Cromer and Andrew J. Grimm and Timothy E. Schlub and Johnson Mak and Miles P. Davenport},
  journal={AIDS},
  year={2016},
  volume={30},
  pages={185–192}
}
Background:HIV recombination has been estimated in vitro using a variety of approaches, and shows a high rate of template switching per reverse transcription event. In-vivo studies of recombination generally measure the accumulation of recombinant strains over time, and thus do not directly estimate a comparable template switching rate. Method:To examine whether the estimated in-vitro template switching rate is representative of the rate that occurs during HIV infection in vivo, we adopted a… Expand
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