Estimating the impact of prehistoric admixture on the genome of Europeans.

@article{Dupanloup2004EstimatingTI,
  title={Estimating the impact of prehistoric admixture on the genome of Europeans.},
  author={Isabelle Dupanloup and Giorgio Bertorelle and Loun{\`e}s Chikhi and Guido Barbujani},
  journal={Molecular biology and evolution},
  year={2004},
  volume={21 7},
  pages={
          1361-72
        }
}
We inferred past admixture processes in the European population from genetic diversity at eight loci, including autosomal, mitochondrial and Y-linked polymorphisms. Admixture coefficients were estimated from multilocus data, assuming that most current populations can be regarded as the result of a hybridization process among four or less potential parental populations. Two main components are apparent in the Europeans' genome, presumably corresponding to the contributions of the first… Expand
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References

SHOWING 1-10 OF 78 REFERENCES
Clines of nuclear DNA markers suggest a largely neolithic ancestry of the European gene pool.
TLDR
It is argued that many mitochondrial lineages whose origin has been traced back to the Paleolithic period probably reached Europe at a later time, and is supported by purely genetic evidence on the levels and patterns of microsatellite diversity, rather than by correlations of biological and nonbiological data. Expand
Tracing European founder lineages in the Near Eastern mtDNA pool.
TLDR
There has been substantial back-migration into the Near East, there was a founder effect or bottleneck associated with the Last Glacial Maximum, 20,000 years ago, and a way to account for multiple dispersals of common sequence types is suggested. Expand
Human Genomic Diversity in Europe: A Summary of Recent Research and Prospects for the Future
TLDR
A phylogenetic tree reconstructed from 95 gene frequencies tested on 26 European samples shows some deviant populations (Lapps, Sardinians, Greeks, Yugoslavs, Basques, Icelanders and Finns) and other weakly structured populations may have a simple interpretation: Europeans have not evolved according to a tree of descent probably because of the major role played by migrations in prehistorical and historical times. Expand
Inferring admixture proportions from molecular data: extension to any number of parental populations.
TLDR
The newly derived multiparental estimator is tested by Monte Carlo simulations and by generating artificial hybrid groups by pooling mtDNA samples from human populations and the general properties of the two-parental estimators seem to be retained. Expand
Y genetic data support the Neolithic demic diffusion model
TLDR
A statistical framework is applied to obtain direct estimates of the relative contributions of European Palaeolithic hunter-gatherers and migrant Near Eastern Neolithic farmers, and argues that the demic diffusion model introduced by Ammerman and Cavalli-Sforza captures the major features of this dramatic episode in European prehistory. Expand
A signal, from human mtDNA, of postglacial recolonization in Europe.
TLDR
The present study shows that the dissection of mtDNA variation into small and well-defined evolutionary units is an essential step in the identification of spatial frequency patterns, and promises to be an efficient strategy for inferring features of human prehistory. Expand
A Recent Shift from Polygyny to Monogamy in Humans Is Suggested by the Analysis of Worldwide Y-Chromosome Diversity
TLDR
It is shown that mismatch distributions and tests of mutation/drift equilibrium based on up to 166 Y-chromosome SNPs, in 46 samples from all continents, also fail to support an increase of the male effective population size. Expand
Indo-European origins: a computer-simulation test of five hypotheses.
TLDR
The genetic structure of current populations speaking Indo-European languages seems to largely reflect a Neolithic expansion, consistent with the hypothesis of a parallel spread of farming technologies and a proto-Indo-European language in the Neolithic. Expand
Geographic patterns of mtDNA diversity in Europe.
TLDR
The distribution of the zones of highest mitochondrial variation (genetic boundaries) confirmed that the Saami are sharply differentiated from an otherwise rather homogeneous set of European samples, and an area of significant clinal variation was identified around the Mediterranean Sea (and not in the north), even though the differences between northern and southern populations were insignificant. Expand
The emerging tree of West Eurasian mtDNAs: a synthesis of control-region sequences and RFLPs.
TLDR
It is shown that the main indigenous North African cluster is a sister group to the most ancient cluster of European mtDNAs, from which it diverged approximately 50,000 years ago. Expand
...
1
2
3
4
5
...