Estimating the cumulative risk of a false-positive test in a repeated screening program.

@article{Xu2004EstimatingTC,
  title={Estimating the cumulative risk of a false-positive test in a repeated screening program.},
  author={Jian-Lun Xu and Richard M. Fagerstrom and Philip C Prorok and Barnett S. Kramer},
  journal={Biometrics},
  year={2004},
  volume={60 3},
  pages={651-60}
}
The goal of screening tests for a chronic disease such as cancer is early detection and treatment with a consequent reduction in mortality from the disease. Screening tests, however, might produce false positive and false-negative results. With an increasing number of screening tests, it is clear that the risk of a false-positive screen, a finding with potentially significant emotional, financial, and health costs, also increases. Elmore et al. (1998, New England Journal of Medicine 338, 1089… CONTINUE READING