Estimating the Impact of Plasma HIV-1 RNA Reductions on Heterosexual HIV-1 Transmission Risk

  title={Estimating the Impact of Plasma HIV-1 RNA Reductions on Heterosexual HIV-1 Transmission Risk},
  author={Jairam R Lingappa and James P. Hughes and Richard S. Wang and Jared M Baeten and Connie L Celum and Glenda Elisabeth Gray and Wendy S. Stevens and Deborah Donnell and Mary Scott Campbell and Carey Farquhar and Max Essex and James I. Mullins and Robert W. Coombs and Helen Rees and Lawrence Corey and Anna Wald},
  booktitle={PloS one},
BACKGROUND The risk of sexual transmission of HIV-1 is strongly associated with the level of HIV-1 RNA in plasma making reduction in HIV-1 plasma levels an important target for HIV-1 prevention interventions. A quantitative understanding of the relationship of plasma HIV-1 RNA and HIV-1 transmission risk could help predict the impact of candidate HIV-1 prevention interventions that operate by reducing plasma HIV-1 levels, such as antiretroviral therapy (ART), therapeutic vaccines, and other non… CONTINUE READING
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ART and Risk of Heterosexual HIV-1 Transmission in HIV-1 Serodiscordant African Couples: A Multinational Prospective Study

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  • 2010
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Determination of HIV transmission linkage in the Partners in Prevention Study. 5th International AIDS Society Conference on HIV Pathogenesis and Treatment: Capetown, South Africa

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1 Excerpt

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