Estimating risk curves for first-degree relatives of patients with Alzheimer’s disease: The REVEAL study

@article{Cupples2004EstimatingRC,
  title={Estimating risk curves for first-degree relatives of patients with Alzheimer’s disease: The REVEAL study},
  author={L. Adrienne Cupples and Lindsay A. Farrer and Adele Dessa Sadovnick and Norman Relkin and Peter Whitehouse and Robert C Green},
  journal={Genetics in Medicine},
  year={2004},
  volume={6},
  pages={192-196}
}
Purpose: The REVEAL study is a randomized, controlled study of the psychological and behavioral impact of APOE disclosure in a risk assessment protocol provided to first degree relatives of patients with Alzheimer’s disease. The protocol presents risk information as cumulative incidence curves. This article describes how these curves were estimated.Methods: Curves were calculated using Bayes’ rule to compute the posterior survival curves incorporating APOE information.Results: A combination of… CONTINUE READING

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Showing 1-10 of 18 references

Risk assessment for Alzheimer’s disease with genetic susceptibility testing: Has the moment arrived

  • RC Green
  • Alzheimer Care Quart
  • 2002

Diagnosis and treatment of Alzheimer’s disease and other dementias

  • RC Green
  • Caddo, OK: Professional Communications;
  • 2001
2 Excerpts

Anticipating response to predictive genetic testing for Alzheimer’s disease: A survey of first-degree relatives

  • JS Roberts
  • Gerontologist
  • 2000

Genetics and the dementia patient

  • LA Farrer
  • The Neurologist
  • 1997

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