Estimating efficacy and drug ED50's using von Frey thresholds: impact of weber's law and log transformation.

Abstract

UNLABELLED The use of von Frey filaments, originally developed by Maximilian von Frey, has become the cornerstone for assaying mechanical sensitivity in animal models and is widely used for human assessment. While there are certain limitations associated with their use that make comparisons between studies not straightforward at times, such as stimulus… (More)
DOI: 10.1016/j.jpain.2012.02.009

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