Estimating division and death rates from CFSE data

@inproceedings{Boer2005EstimatingDA,
  title={Estimating division and death rates from CFSE data},
  author={Rob J. De Boer and Alan S. Perelson},
  year={2005}
}
The division tracking dye, carboxyfluorescin diacetate succinimidyl ester (CFSE) is currently the most informative labeling technique for characterizing the division history of cells in the immune system. Gett and Hodgkin (Nat. Immunol. 1 (2000) 239–244) have proposed to normalize CFSE data by the 2-fold expansion that is associated with each division, and have argued that the mean of the normalized data increases linearly with time, t, w th a slope reflecting the division ratep. We develop a… CONTINUE READING
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