Estimating autozygosity from high-throughput information: effects of SNP density and genotyping errors

@inproceedings{Ferenakovi2013EstimatingAF,
  title={Estimating autozygosity from high-throughput information: effects of SNP density and genotyping errors},
  author={Maja Feren{\vc}akovi{\'c} and Johann S{\"o}lkner and Ino Curik},
  booktitle={Genetics Selection Evolution},
  year={2013}
}
Runs of homozygosity are long, uninterrupted stretches of homozygous genotypes that enable reliable estimation of levels of inbreeding (i.e., autozygosity) based on high-throughput, chip-based single nucleotide polymorphism (SNP) genotypes. While the theoretical definition of runs of homozygosity is straightforward, their empirical identification depends on the type of SNP chip used to obtain the data and on a number of factors, including the number of heterozygous calls allowed to account for… CONTINUE READING
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