Estimating Time of Last Oral Ingestion of Cannabis From Plasma THC and THCCOOH Concentrations

  title={Estimating Time of Last Oral Ingestion of Cannabis From Plasma THC and THCCOOH Concentrations},
  author={M. Huestis and M. ElSohly and Wesenyalsh Nebro and A. Barnes and R. A. Gustafson and M. Smith},
  journal={Therapeutic Drug Monitoring},
  • M. Huestis, M. ElSohly, +3 authors M. Smith
  • Published 2006
  • Medicine
  • Therapeutic Drug Monitoring
  • Estimating the time of last cannabis use is important in assessing possible impairment of drivers involved in accidents, in verifying accuracy of court testimony and in the future, helpful in therapeutic monitoring of cannabis agonists. In 1992, Huestis et al developed model 1, based on plasma Δ9-tetrahydrocannabinol (THC) concentrations, and model 2, on plasma 11-nor-9-carboxy-Δ9-tetrahydrocannbinol/THC ratios, that predicted 95% confidence intervals for time of last cannabis use. These models… CONTINUE READING
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