Estimating Heritability from Twin Studies.

@article{Grasby2017EstimatingHF,
  title={Estimating Heritability from Twin Studies.},
  author={Katrina L Grasby and Karin J H Verweij and Miriam A Mosing and Brendan P. Zietsch and Sarah E. Medland},
  journal={Methods in molecular biology},
  year={2017},
  volume={1666},
  pages={
          171-194
        }
}
This chapter describes how the heritability of a trait can be estimated using data collected from pairs of twins. The principles of the classical twin design are described, followed by the assumptions, and some possible extensions of the design. In the second part of this chapter, two example scripts are presented and the basic steps for estimating heritability using the statistical program OpenMx are explained. OpenMx and the scripts used for this chapter can be downloaded so that readers can… CONTINUE READING
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