Estimating Consumer Exposure to PFOS and PFOA

  title={Estimating Consumer Exposure to PFOS and PFOA},
  author={David Trudel and Leah S. Horowitz and Matthias Wormuth and Martin Scheringer and Ian T. Cousins and Konrad Hungerb{\"u}hler},
  journal={Risk Analysis},
Perfluorinated compounds have been used for more than 50 years as process aids, surfactants, and for surface protection. This study is a comprehensive assessment of consumer exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) from a variety of environmental and product‐related sources. To identify relevant pathways leading to consumer exposure to PFOS and PFOA a scenario‐based approach has been applied. Scenarios represent realistic situations where age‐ and gender… 
A Review of the Pathways of Human Exposure to Poly- and Perfluoroalkyl Substances (PFASs) and Present Understanding of Health Effects
Understanding of sources and trends in human exposure to poly- and perfluoroalkyl substances (PFASs) and epidemiologic evidence for impacts on cancer, immune function, metabolic outcomes, and neurodevelopment are reviewed.
Risk to human health related to the presence of perfluorooctane sulfonic acid and perfluorooctanoic acid in food
For PFOS, the increase in serum total cholesterol in adults, and the decrease in antibody response at vaccination in children were identified as the critical effects and the CONTAM Panel established a tolerable weekly intake (TWI) of 13 ng/kg body weight (bw) per week for PFOS and 6 ng/ kg bw for PFOA.
An assessment of the exposure of Americans to perfluorooctane sulfonate: A comparison of estimated intake with values inferred from NHANES data
  • P. Egeghy, M. Lorber
  • Psychology
    Journal of Exposure Science and Environmental Epidemiology
  • 2011
A model that assesses exposure to perfluorooctane sulfonate (PFOS) and its precursors from both an intake and a body burden perspective and combines the two with a simple pharmacokinetic (PK) model is demonstrated and lends validity to the proposed framework.
Human dietary exposure to per- and poly-fluoroalkyl substances (PFASs)
Per- and polyfluoroalkyl substances (PFASs) are a class of emerging contaminants with numerous industrial and commercial applications. Within this class the best studied substances are the
Risk to human health related to the presence of perfluoroalkyl substances in food
The CONTAM Panel concluded that parts of the European population exceed this tolerable weekly intake (TWI) of 4.4 ng/kg bw per week, which is of concern, and protects against other potential adverse effects observed in humans.
Occurrence of Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoate (PFOA) in Aquatic Systems from Asia
Perfluorinated compounds (PFCs) are man-made fluorinated hydrocarbons, which are very persistent in the environment. Being the most important PFC, perfluorooctane sulfonate (PFOS) and


Exposure assessment and risk characterization for perfluorooctanoate in selected consumer articles.
Exposures to PFO during consumer use of the articles evaluated in this study are not expected to cause adverse human health effects in infants, children, adolescents, adult residents, or professionals nor result in quantifiable levels of PFO in human serum.
Human exposure to perfluorinated chemicals through the diet: intake of perfluorinated compounds in foods from the Catalan (Spain) market.
The current results do not justify dietary intake as the main route of exposure governing blood concentrations of other PFCs, and a correlation between dietary intake and blood levels of PFOS is suggested.
Occurrence of perfluorinated substances in an adult German population in southern Bavaria
The data suggest that the current exposure of the adult German population is lower than the Exposure of the US and Canadian population, and the sources of human exposure are currently not well understood.
Sources, fate and transport of perfluorocarboxylates.
Transport pathways for PFCAs in the environment were reviewed, and it was concluded that, in addition to atmospheric transport/degradation of precursors, atmospheric and ocean water transport of the PFCA themselves could significantly contribute to their long-range transport.
Survey on PFOS and other perfluorinated compounds in Dutch fish and shellfish
Perfluorinated compounds (PFCs) are used in a wide variety of applications as a surfactant because of their ‘wetting’ properties. Other applications include moisture, stain and fat repellency for
Concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) in vacuum cleaner dust collected in Japanese homes.
It was ascertained that PFOS and PFOA were present in the dust in homes, and that the absorption of the dust could be one of the exposure pathways of the PFOS/PFOA to humans.
Health risks in infants associated with exposure to perfluorinated compounds in human breast milk from Zhoushan, China.
No statistically significant correlation was found between concentrations of either PFOS or PFOA and maternal age, weight, or infant weight, but rate of consumption of fish was found to be positively correlated with PFNA, PFDA, and PFUnDA concentrations.
Biological monitoring of polyfluoroalkyl substances: A review.
The pattern of contamination in wildlife varied among species and locations suggesting multiple emission sources and knowledge gaps with respect to the transport, accumulation, biodegradation, temporal/spatial trends and PFS precursors have been identified.