Estimates of the chromium(VI) reducing capacity in human body compartments as a mechanism for attenuating its potential toxicity and carcinogenicity.

@article{Flora1997EstimatesOT,
  title={Estimates of the chromium(VI) reducing capacity in human body compartments as a mechanism for attenuating its potential toxicity and carcinogenicity.},
  author={S. De Flora and A. Camoirano and M. Bagnasco and C. Bennicelli and G. E. Corbett and B. Kerger},
  journal={Carcinogenesis},
  year={1997},
  volume={18 3},
  pages={
          531-7
        }
}
Estimates of the overall reducing capacity of hexavalent chromium(VI) in some human body compartments were made by relating the specific reducing activity of body fluids, cell populations or organs to their average volume, number, or weight. Although these data do not have absolute precision or universal applicability, they provide a rationale for predicting and interpreting the health effects of chromium(VI). The available evidence strongly indicates that chromium(VI) reduction in body fluids… Expand
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References

SHOWING 1-10 OF 54 REFERENCES
Hexavalent chrome: threshold concept for carcinogenicity.
  • R. Jones
  • Chemistry, Medicine
  • Biomedical and environmental sciences : BES
  • 1990
  • 22
Metabolic reduction of chromium as a threshold mechanism limiting its in vivo activity.
  • 26
Uptake of 51Cr-chromate by human erythrocytes-a role of glutathione.
  • 62
Chromium bond detection in isolated erythrocytes: a new principle of biological monitoring of exposure to hexavalent chromium
  • 87
Genotoxicity of chromium compounds. A review.
  • 409
...
1
2
3
4
5
...