Estimates of Within-Subject Biological Variation of Protein C, Antithrombin, Protein S Free, Protein S Activity, and Activated Protein C Resistance in Pregnant Women.

@article{Kristoffersen2017EstimatesOW,
  title={Estimates of Within-Subject Biological Variation of Protein C, Antithrombin, Protein S Free, Protein S Activity, and Activated Protein C Resistance in Pregnant Women.},
  author={A. Kristoffersen and P. H. Petersen and T. R{\o}raas and S. Sandberg},
  journal={Clinical chemistry},
  year={2017},
  volume={63 4},
  pages={
          898-907
        }
}
BACKGROUND In pregnancy, interpretation of results from coagulation parameters can be difficult because of the procoagulant physiological changes. The aim of this study was to describe the course of 5 coagulation parameters (thrombophilia markers) in healthy pregnancies, and to estimate and compare the within-subject biological variation (CVI) of these parameters in healthy pregnant and nonpregnant women. METHODS Blood samples were obtained every 4th week during pregnancy and 3 samples after… Expand
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