Estimated pulmonary artery systolic pressure and sickle cell disease: a meta‐analysis and systematic review

@article{Caughey2015EstimatedPA,
  title={Estimated pulmonary artery systolic pressure and sickle cell disease: a meta‐analysis and systematic review},
  author={M. Caughey and C. Poole and K. Ataga and A. Hinderliter},
  journal={British Journal of Haematology},
  year={2015},
  volume={170}
}
Many studies report estimated pulmonary artery systolic pressure (ePASP) in patients with sickle cell disease (SCD) screened by echocardiography. To better understand the prevalence and outcomes of elevated ePASP in clinically stable SCD patients, we conducted a random‐effects meta‐analysis. A total of 45 studies, representing 15 countries and including 6109 individuals, met our inclusion criteria. In most (70%) studies, elevated ePASP was defined by a tricuspid regurgitant velocity of 2·5 m/s… Expand
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