Estimated maximal and current brain volume predict cognitive ability in old age

@inproceedings{Royle2013EstimatedMA,
  title={Estimated maximal and current brain volume predict cognitive ability in old age},
  author={Natalie A. Royle and Tom Booth and Maria Del C Vald{\'e}s Hern{\'a}ndez and Lars Penke and Catherine Murray and Alan J. Gow and Susana Mu{\~n}oz Maniega and John M Starr and Mark E. Bastin and Ian J. Deary and Joanna M. Wardlaw},
  booktitle={Neurobiology of Aging},
  year={2013}
}
Brain tissue deterioration is a significant contributor to lower cognitive ability in later life; however, few studies have appropriate data to establish how much influence prior brain volume and prior cognitive performance have on this association. We investigated the associations between structural brain imaging biomarkers, including an estimate of maximal brain volume, and detailed measures of cognitive ability at age 73 years in a large (N = 620), generally healthy, community-dwelling… CONTINUE READING

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