Estimated lean mass and fat mass differentially affect femoral bone density and strength index but are not FRAX independent risk factors for fracture.

@article{Leslie2014EstimatedLM,
  title={Estimated lean mass and fat mass differentially affect femoral bone density and strength index but are not FRAX independent risk factors for fracture.},
  author={William D Leslie and Eric S. Orwoll and Carrie M Nielson and Suzanne Nicole Morin and Sumit Ranjan Majumdar and Helena Johansson and Anders Od{\'e}n and Eugene V. McCloskey and J. A. Kanis},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2014},
  volume={29 11},
  pages={2511-9}
}
Although increasing body weight has been regarded as protective against osteoporosis and fractures, there is accumulating evidence that fat mass adversely affects skeletal health compared with lean mass. We examined skeletal health as a function of estimated total body lean and fat mass in 40,050 women and 3600 men age ≥50 years at the time of baseline dual-energy X-ray absorptiometry (DXA) testing from a clinical registry from Manitoba, Canada. Femoral neck bone mineral density (BMD), strength… CONTINUE READING
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