Estazolam Treatment of Insomnia in Generalized Anxiety Disorder: A Placebo‐Controlled Study

@article{Post1991EstazolamTO,
  title={Estazolam Treatment of Insomnia in Generalized Anxiety Disorder: A Placebo‐Controlled Study},
  author={Gary L. Post and Roger Patrick and John E. Crowder and John P. Houston and J. Michael Ferguson and Robert J. Bielski and Linda Bailey and Helene Pearlman and Vincent Shu and Mark W. Pierce},
  journal={Journal of Clinical Psychopharmacology},
  year={1991},
  volume={11},
  pages={249–253}
}
Estazolam, a triazolobenzodiazepine with an intermediate elimination half-life, has been shown previously to be an effective and safe hypnotic in insomniacs without concomitant psychiatric illness. Our study of the efficacy of estazolam in patients with insomnia associated with generalized anxiety disorder began when 108 patients meeting criteria for generalized anxiety disorder (mean total score of Hamilton Rating Scale for Anxiety [HAM-A] = 22.0 ± 3.1 [SD]) and insomnia were given single… 
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