Establishment of two human prostate cancer cell lines derived from a single bone metastasis.

@article{Navone1997EstablishmentOT,
  title={Establishment of two human prostate cancer cell lines derived from a single bone metastasis.},
  author={Nora Navone and Matilde Oliv{\'e} and Mustafa Ozen and Rodney Davis and P. Brunny Troncoso and Shi Ming Tu and Dennis A Johnston and Allan J. Pollack and Sen Pathak and Andrew von Eschenbach and Christopher J. Logothetis},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={1997},
  volume={3 12 Pt 1},
  pages={2493-500}
}
Human prostate cancer cell lines are particularly difficult to establish, and most existing cell lines do not exhibit features commonly seen in human prostate cancer. Most available models either grow only in vivo as xenografts or are androgen insensitive and fail to express prostate-specific antigen (PSA). The lack of functionally relevant model systems of advanced prostate cancer has limited prostate cancer research and therapy development. Of 30 processed samples derived from patients with… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 89 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 29 references

Carcinoma of the prostate

  • R F.Gittes.
  • N. Engl. J. Med.
  • 1991
Highly Influential
4 Excerpts

Characterization of a novel androgen - sensitive . prostate - specific antigen - producing prostate carcinoma xenograft : LuCaP 23

  • W. J. Ellis, R. L. Vassella, +5 authors P. H. Lange
  • Clin . Cancer Res .
  • 1996

Characterization of a novel androgen-sensitive. prostate-specific antigen-producing prostate carcinoma

  • Ellis, R.L.W.J.. Vassella, +5 authors P. H. Lange
  • xenograft: LuCaP 23. Clin. Cancer Res.,
  • 1996
2 Excerpts

Dussurget . 0 . , and Roulland - Dussoix , D . Rapid , sensitive PCR - based detection of mycoplasmas in simulated samples of animal sera

  • J. H. Zar
  • Biostatistical Analysis
  • 1996

Similar Papers

Loading similar papers…