Establishment of three-dimensional tissue-engineered bone constructs under microgravity-simulated conditions.

@article{Jin2010EstablishmentOT,
  title={Establishment of three-dimensional tissue-engineered bone constructs under microgravity-simulated conditions.},
  author={Fang Chun Jin and Yongjie Zhang and Kun Xuan and Dongni He and Tianzheng Deng and Liang Tang and Wei Lu and Yinzhong Duan},
  journal={Artificial organs},
  year={2010},
  volume={34 2},
  pages={118-25}
}
Bone constructs have been grown in vitro with use of isolated cells, biodegradable polymer scaffolds, and bioreactors. In our work, the relationships between the composition and mechanical properties of engineered bone constructs were studied by culturing bone marrow mesenchymal stem cells (BMSCs) on ceramic bovine bone scaffolds in different environments: static flasks and dynamic culture system in rotating vessels-which was a National Aeronautics and Space Administration-recommended, ground… CONTINUE READING