Establishment of the MAVER-1 cell line, a model for leukemic and aggressive mantle cell lymphoma.

@article{Zam2006EstablishmentOT,
  title={Establishment of the MAVER-1 cell line, a model for leukemic and aggressive mantle cell lymphoma.},
  author={Alberto Zam{\`o} and German Ott and Tiemo Katzenberger and Patrick Adam and Claudia Parolini and Aldo Scarpa and Maurizio Lestani and Fabio Menestrina and Marco Chilosi},
  journal={Haematologica},
  year={2006},
  volume={91 1},
  pages={
          40-7
        }
}
BACKGROUND AND OBJECTIVES Mantle cell lymphoma (MCL) cell lines are difficult to generate; only nine lines have been described so far and few of them have been thoroughly characterized. DESIGN AND METHODS We established MAVER-1, a new MCL cell line, obtained from a leukemic MCL harboring both a t(11;14) translocation and a MYC rearrangement, and used immunohistochemistry, flow cytometry, molecular biology and cytogenetic techniques in order to characterize the cell line precisely. RESULTS… CONTINUE READING

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