Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract

@inproceedings{Damhofer2015EstablishmentOP,
  title={Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract},
  author={Helene Damhofer and Eva A. Ebbing and Anne Steins and L. Welling and Johanna A. M. G. Tol and Kausilia K Krishnadath and Tom van Leusden and Marc Joan Van de Vijver and Marc Gerard Besselink and Olivier R. C. Busch and Mark I. van Berge Henegouwen and Otto M van Delden and Sybren L. Meijer and Frederike Dijk and Jan Paul Medema and Hanneke W. M. van Laarhoven and Maarten F Bijlsma},
  booktitle={Journal of Translational Medicine},
  year={2015}
}
The upper gastrointestinal tract is home to some of most notorious cancers like esophagogastric and pancreatic cancer. Several factors contribute to the lethality of these tumors, but one that stands out for both tumor types is the strong inter- as well as intratumor heterogeneity. Unfortunately, genetic tumor models do not match this heterogeneity, and for esophageal cancer no adequate genetic models exist. To allow for an improved understanding of these diseases, tissue banks with sufficient… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
11 Citations
29 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 29 references

Similar Papers

Loading similar papers…