Establishment of human iPSC-based models for the study and targeting of glioma initiating cells

Abstract

Glioma tumour-initiating cells (GTICs) can originate upon the transformation of neural progenitor cells (NPCs). Studies on GTICs have focused on primary tumours from which GTICs could be isolated and the use of human embryonic material. Recently, the somatic genomic landscape of human gliomas has been reported. RTK (receptor tyrosine kinase) and p53… (More)
DOI: 10.1038/ncomms10743

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@inproceedings{SanchoMartinez2016EstablishmentOH, title={Establishment of human iPSC-based models for the study and targeting of glioma initiating cells}, author={Ignacio Sancho-Martinez and Emmanuel Nivet and Yun Xia and Tomoaki Hishida and Aitor Aguirre and Alejandro C Ocampo and Li Ma and R A Morey and Marie N. Krause and Andreas Zembrzycki and Olaf Ansorge and Eric Vazquez-Ferrer and Ilir Dubova and Pradeep Reddy and David Lam and Yuriko Hishida and Min-Zu Wu and Concepci{\'o}n Rodr{\'i}guez Esteban and Dennis D. M. O'Leary and Geoffrey M. Wahl and Inder M Verma and Louise Chang Laurent and Juan Carlos Izpisua Belmonte}, booktitle={Nature communications}, year={2016} }