Establishment of cell-cell cross talk in the epididymis: control of luminal acidification.

Abstract

Male infertility is often caused by sperm that have low motility and interact poorly with the oocyte. Spermatozoa acquire these crucial functions in the epididymis. A low luminal bicarbonate (HCO(3)(-)) concentration and low pH keep sperm quiescent during their maturation and storage in this organ. This review describes how epididymal epithelial cells work… (More)
DOI: 10.2164/jandrol.111.012971

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