Establishment of a triple co-culture in vitro cell models to study intestinal absorption of peptide drugs.

Abstract

In vitro cell culture models for studying oral drug absorption during early stages of drug development have become a useful tool in drug discovery and development, with respect to substance throughput and reproducibility. The aim of this study was to establish an in vitro cellular model based on human colon carcinoma Caco-2, mucus-producing HT29, and Raji B… (More)
DOI: 10.1016/j.ejpb.2012.10.003

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