Establishment of a superficial skin infection model in mice by using Staphylococcus aureus and Streptococcus pyogenes.

@article{Kugelberg2005EstablishmentOA,
  title={Establishment of a superficial skin infection model in mice by using Staphylococcus aureus and Streptococcus pyogenes.},
  author={Elisabeth Kugelberg and Tobias Norstr{\"o}m and Thomas K. Petersen and Tore Duvold and Dan I Andersson and Diarmaid Hughes},
  journal={Antimicrobial agents and chemotherapy},
  year={2005},
  volume={49 8},
  pages={3435-41}
}
A new animal model for the purpose of studying superficial infections is presented. In this model an infection is established by disruption of the skin barrier by partial removal of the epidermal layer by tape stripping and subsequent application of the pathogens Staphylococcus aureus and Streptococcus pyogenes. The infection and the infection route are purely topical, in contrast to those used in previously described animal models in mice, such as the skin suture-wound model, where the… CONTINUE READING

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