Establishment of a pipeline to analyse non-synonymous SNPs in Bos taurus

@article{Lee2006EstablishmentOA,
  title={Establishment of a pipeline to analyse non-synonymous SNPs in Bos taurus},
  author={Michael A. Lee and Orla Mary Keane and Belinda C. Glass and Tim R. Manley and Neil Cullen and Ken G. Dodds and Alan F. McCulloch and Chris A. Morris and Mark J. Schreiber and Jonathan Warren and Amonida Zadissa and Theresa Wilson and John C. McEwan},
  journal={BMC Genomics},
  year={2006},
  volume={7},
  pages={298 - 298}
}
Single nucleotide polymorphisms (SNPs) are an abundant form of genetic variation in the genome of every species and are useful for gene mapping and association studies. Of particular interest are non-synonymous SNPs, which may alter protein function and phenotype. We therefore examined bovine expressed sequences for non-synonymous SNPs and validated and tested selected SNPs for their association with measured traits. Over 500,000 public bovine expressed sequence tagged (EST) sequences were used… CONTINUE READING