Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion.

@article{Zhang2010EstablishmentOA,
  title={Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion.},
  author={Jingjing Zhang and J{\"o}rg Piontek and Hartwig Wolburg and Christian Piehl and Martin Liss and C{\'e}cile Otten and Annabel Christ and Thomas E. Willnow and Ingolf E Blasig and Salim Abdelilah-Seyfried},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2010},
  volume={107 4},
  pages={1425-30}
}
Lumen expansion driven by hydrostatic pressure occurs during many morphogenetic processes. Although it is well established that members of the Claudin family of transmembrane tight junction proteins determine paracellular tightness within epithelial/endothelial barrier systems, functional evidence for their role in the morphogenesis of lumenized organs has… CONTINUE READING