Establishment of a high sensitivity plasma assay for human pentraxin3 as a marker for unstable angina pectoris.

  title={Establishment of a high sensitivity plasma assay for human pentraxin3 as a marker for unstable angina pectoris.},
  author={Kenji Inoue and Akira Sugiyama and Patrick C. Reid and Yukio Ito and Katsumi Miyauchi and Sei Mukai and Mina Sagara and Kyoko Miyamoto and Hirokazu Satoh and Isao Kohno and T. Kurata and Hiroshi Ota and Alberto Mantovani and Takao Hamakubo and Hiroyuki Daida and Tatsuhiko Kodama},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  volume={27 1},
OBJECTIVE Plasma pentraxin 3 (PTX3) levels are increased in patients with acute myocardial infarction, yet its involvement in unstable angina pectoris (UAP) remains unclear. To critically evaluate the role of PTX3 in UAP, a sensitive and precise measurement of PTX3 concentration is needed. METHODS AND RESULTS We established a high sensitive plasma ELISA assay system for the detection of PTX3 using monoclonal antibodies. The lower limit of detection of our ELISA was 0.1 ng/mL, sensitivity far… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 101 extracted citations

Inflammation and Atherosclerosis

Springer Vienna • 2012
View 20 Excerpts
Highly Influenced

Clinical Use of Pentraxin 3 : A Review

View 7 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 24 references

Clinical management of metabolic syndrome: report of the Am Heart Association/ National Heart, Lung, and Blood Institute/Am Diabetes Association conference on scientific issues related to management

SM Grundy, B Hansen, SC JrSmith, JI Cleeman, RA. Kahn
Arterioscler Thromb Vasc Biol • 2004

Heart Disease, a Text Book of Cardiovascular Medicine (fourth edition)

E. Braunwald
Elseveir; Philadelphia, • 2004

Brachial-ankle pulse wave velocity as a marker of atherosclerotic vascular damage and cardiovascular risk.

Hypertension research : official journal of the Japanese Society of Hypertension • 2003

Similar Papers

Loading similar papers…