Establishment of a follicular lymphoma cell line (FLK-1) dependent on follicular dendritic cell-like cell line HK


A novel cell line, FLK-1, was established from bone marrow cells of a patient with follicular lymphoma by means of co-culture with follicular dendritic cell (FDC)-like cell line HK. Immunophenotypic analysis showed that FLK-1 expressed CD10, CD19, CD20, CD38, IgG and HLA-DR, which is a typical feature of germinal center B cells. Cytogenetic analysis of FLK… (More)
DOI: 10.1038/sj.leu.2402002


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