Establishment of a New Quality Control and Vaccine Safety Test for Influenza Vaccines and Adjuvants Using Gene Expression Profiling

Abstract

We have previously identified 17 biomarker genes which were upregulated by whole virion influenza vaccines, and reported that gene expression profiles of these biomarker genes had a good correlation with conventional animal safety tests checking body weight and leukocyte counts. In this study, we have shown that conventional animal tests showed varied and… (More)
DOI: 10.1371/journal.pone.0124392

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@inproceedings{Momose2015EstablishmentOA, title={Establishment of a New Quality Control and Vaccine Safety Test for Influenza Vaccines and Adjuvants Using Gene Expression Profiling}, author={Haruka Momose and Takuo Mizukami and Madoka Kuramitsu and K. Takizawa and Atsuko Masumi and Kumiko Araki and Keiko Furuhata and K. Yamaguchi and Isao Hamaguchi}, booktitle={PloS one}, year={2015} }