Establishment and molecular characterization of five cell lines derived from renal and extrarenal malignant rhabdoid tumors.

Abstract

Malignant rhabdoid tumor (MRT) is a rare, enigmatic childhood cancer characterized by extreme aggressiveness and resistance to chemotherapy. To understand better the origin of the tumor and the mechanisms by which it develops and resists treatment, five cell lines were established from patients presenting with MRT (two renal and three extrarenal tumors… (More)

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