Establishment and long-term xenografting of human pancreatic carcinomas in immunosuppressed mice: changes and stability in morphology, DNA ploidy and proliferation activity

@article{Bocsi1999EstablishmentAL,
  title={Establishment and long-term xenografting of human pancreatic carcinomas in immunosuppressed mice: changes and stability in morphology, DNA ploidy and proliferation activity},
  author={J{\'o}zsef Bocsi and Attila Zalatnai},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={1999},
  volume={125},
  pages={9-19}
}
The prognosis of pancreatic carcinoma is grave, therefore the experimental model systems remain major tools for testing new treatment modalities. We have developed human pancreatic cancer lines growing in immunosuppressed mice and characterized them by morphological and flow-cytometric studies. Immunosuppression has been achieved in young (4-week-old) CBA… CONTINUE READING