Establishment and identification of induced pluripotent stem cells in liver cancer patients.

@article{Zhang2014EstablishmentAI,
  title={Establishment and identification of induced pluripotent stem cells in liver cancer patients.},
  author={Da-ming Zhang and Jian-Jun Li and Peng Yan and Jian-ting Hu},
  journal={Asian Pacific journal of tropical medicine},
  year={2014},
  volume={7 4},
  pages={
          253-6
        }
}
OBJECTIVE To induce pluripotent stem (IPS) cells from fibrocytes that are separated from liver cancer patients. METHODS The fibrocytes were reprogrammed to IPS cells by lentiviral vector, stained and identified by immunohistochemistry. RESULTS The IPS cells were successfully established from fibrocytes after infection, and IPS cell clones formed in round shape under a microscopy. The induction rate was 0.013%±0.007%. No tumor formed at the back of nude mice within 8 weeks after the… CONTINUE READING
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